Publicaciones

Evaluation and validation of a PrintrLab-based LAMP assay to identify Trypanosoma cruzi in newborns in Bolivia: a proof-of-concept study.
Rojas Panozo L, Rivera Nina S, Wehrendt DP, Casellas A, Pinto L, Mendez S, Kuo Ch, Lozano DF, Ortiz L, Pinazo M, Picado A, Sanz S, Abril M, Gascon J, Wong S, Schijman AG, Torrico F, Alonso-Padilla J.
The Lancet Microbe https://doi.org/10.1016/S2666-5247(24)00110-1

Retrospect, advances and challenges in Chagas disease diagnosis: a comprehensive review
Schijman AG, Alonso-Padilla J, Britto C, Herrera Bernal CP.
The Lancet Regional Health – Americas https://doi.org/10.1016/j.lana.2024.100821

Development and Evaluation of a Three-Dimensional Printer-Based DNA Extraction Method Coupled to Loop Mediated Isothermal Amplification for Point-of-Care Diagnosis of Congenital Chagas Disease in Endemic Regions.
Wehrendt DP, Alonso-Padilla J, Liu B, Rojas Panozo L, Rivera Nina S, Pinto L, Lozano D, Picado A, Abril M, Pinazo MJ, Gascon J, Torrico F, Wong S, Schijman AG.
J Mol Diagn. 2021 doi: 10.1016/j.jmoldx.2020.12.007

Characterization and Follow-Up of Trypanosoma cruzi Natural Populations Refractory to Etiological Chemotherapy in Oral Chagas Disease Patients.
Muñoz-Calderón A, Díaz-Bello Z, Alarcón de Noya B, Noya-González OO, Schijman AG.
Frontiers in Cellular and Infection Microbiology 2021 doi: 10.3389/fcimb.2021.665063

Toward the Establishment of a Single Standard Curve for Quantification of Trypanosoma cruzi Natural Populations Using a Synthetic Satellite Unit DNA Sequence.
Muñoz-Calderón A, Silva-Gomes NL, Apodaca S, Alarcón de Noya B, Díaz-Bello Z, Rocha Quintino Souza L, Dias Tavares Costa A, Britto C, Cruz Moreira O, Schijman AG.
J Mol Diagn. 2021 May;23(5):521-531. doi: 10.1016/j.jmoldx.2021.01.007

Development and Evaluation of a Three-Dimensional Printer-Based DNA Extraction Method Coupled to Loop Mediated Isothermal Amplification for Point-of-Care Diagnosis of Congenital Chagas Disease in Endemic Regions.
Wehrendt DP, Alonso-Padilla J, Liu B, Rojas Panozo L, Rivera Nina S, Pinto L, Lozano D, Picado A, Abril M, Pinazo MJ, Gascon J, Torrico F, Wong S, Schijman AG.
J Mol Diagn. 2020 Dec 30:S1525-1578(20)30615-2. doi: 10.1016/j.jmoldx.2020.12.007. Online ahead of print.

Short-course Benznidazole treatment to reduce Trypanosoma cruzi parasitic load in women of reproductive age (BETTY): a non-inferiority randomized controlled trial study protocol.
Cafferata ML, Toscani MA, Althabe F, Belizán JM, Bergel E, Berrueta M, Capparelli EV, Ciganda Á, Danesi E, Dumonteil E, Gibbons L, Gulayin PE, Herrera C, Momper JD, Rossi S, Shaffer JG, Schijman AG, Sosa-Estani S, Stella CB, Klein K, Buekens P.
Reprod Health. 2020 Aug 24;17(1):128. doi: 10.1186/s12978-020-00972-1.

Trypanosoma cruzi loop-mediated isothermal amplification (Trypanosoma cruzi Loopamp) kit for detection of congenital, acute and Chagas disease reactivation.
Besuschio SA, Picado A, Muñoz-Calderón A, Wehrendt DP, Fernández M, Benatar A, Diaz-Bello Z, Irurtia C, Cruz I, Ndung’u JM, Cafferata ML, Montenegro G, Sosa Estani S, Lucero RH, Alarcón de Noya B, Longhi SA, Schijman AG.
PLoS Negl Trop Dis. 2020 Aug 14;14(8):e0008402. doi: 10.1371/journal.pntd.0008402. eCollection 2020 Aug.

Real-time polymerase chain reaction based algorithm for differential diagnosis of Kinetoplastidean species of zoonotic relevance.
Muñoz-Calderón A, Wehrendt D, Cura C, Gómez-Bravo A, Abril M, Giammaria M, Lucero RH, Schijman AG.
Infect Genet Evol. 2020 Sep;83:104328. doi: 10.1016/j.meegid.2020.104328. Epub 2020 Apr 21.

Development and evaluation of a duplex TaqMan qPCR assay for detection and quantification of Trypanosoma cruzi infection in domestic and sylvatic reservoir hosts.
Wehrendt DP, Gómez-Bravo A, Ramirez JC, Cura C, Pech-May A, Ramsey JM, Abril M, Guhl F, Schijman AG.
Parasit Vectors. 2019 Nov 29;12(1):567. doi: 10.1186/s13071-019-3817-9.

Congenital Transmission of Trypanosoma cruzi: A Review About the Interactions Between the Parasite, the Placenta, the Maternal and the Fetal/Neonatal Immune Responses.
Kemmerling U, Osuna A, Schijman AG, Truyens C.
Front Microbiol. 2019 Aug 14;10:1854. doi: 10.3389/fmicb.2019.01854. eCollection 2019.

Role of nucleic acid amplification assays in monitoring treatment response in chagas disease: Usefulness in clinical trials.
Sulleiro E, Muñoz-Calderon A, Schijman AG.
Acta Trop. 2019 Nov;199:105120. doi: 10.1016/j.actatropica.2019.105120. Epub 2019 Jul 31.

Detection of anti-Trypanosoma cruzi antibodies by chimeric antigens in chronic Chagas disease-individuals from endemic South American countries.
Del-Rei RP, Leony LM, Celedon PAF, Zanchin NIT, Reis MGD, Gomes YM, Schijman AG, Longhi SA, Santos FLN.
PLoS One. 2019 Apr 18;14(4):e0215623. doi: 10.1371/journal.pone.0215623. eCollection 2019.

Association study between CCR2-CCR5 genes polymorphisms and chronic Chagas heart disease in Wichi and in admixed populations from Argentina.
Juiz NA, Estupiñán E, Hernández D, Garcilazo A, Chadi R, Morales Sanfurgo G, Schijman AG, Longhi SA, González CI.
PLoS Negl Trop Dis. 2019 Jan 16;13(1):e0007033. doi: 10.1371/journal.pntd.0007033. eCollection 2019 Jan.

Introducing automation to the molecular diagnosis of Trypanosoma cruzi infection: A comparative study of sample treatments, DNA extraction methods and real-time PCR assays.
Abras A, Ballart C, Llovet T, Roig C, Gutiérrez C, Tebar S, Berenguer P, Pinazo MJ, Posada E, Gascón J, Schijman AG, Gállego M, Muñoz C.
PLoS One. 2018 Apr 17;13(4):e0195738. doi: 10.1371/journal.pone.0195738.

New insights into Trypanosoma cruzi evolution, genotyping and molecular diagnostics from satellite DNA sequence analysis.
Ramírez JC, Torres C, Curto MLA, Schijman AG. (2017)
PLoS Negl Trop Dis. PMID: 29253860 PMCID: PMC5749901 DOI: 10.1371/journal.pntd.0006139

Analytical sensitivity and specificity of a loop-mediated isothermal amplification (LAMP) kit prototype for detection of Trypanosoma cruzi DNA in human blood samples.
Besuschio SA, Llano Murcia M, Benatar AF, Monnerat S, Cruz Mata I, Picado de Puig A, Curto MLÁ, Kubota Y, Wehrendt DP, Pavia P, Mori Y, Puerta C, Ndung’u JM, Schijman AG. (2017)
PLoS Negl Trop Dis 11(7): e0005779. https://doi.org/10.1371/journal.pntd.0005779