Dopamine D2 receptors in WFS1-neurons regulate food-seeking and avoidance behaviors
Castell L, Le Gall V, Cutando L, Petit CP, Puighermanal E, Makrini-Maleville L, Kim HR, Jercog D, Tarot P, Tassou A, Harrus AG, Rubinstein M, Nouvian R, Rivat C, Besnard A, Trifilieff P, Gangarossa G, Janak PH, Herry C, Valjent E.
Prog Neuropsychopharmacol Biol Psychiatry. 2024 Feb 8;129:110883. doi: 10.1016/j.pnpbp.2023.110883. Epub 2023 Oct 17.

Characterization of Novel Trypanosoma cruzi-Specific Antigen with Potential Use in the Diagnosis of Chagas Disease
Ossowski MS, Gallardo JP, Niborski LL, Rodríguez-Durán J, Lapadula WJ, Juri Ayub M, Chadi R, Hernandez Y, Fernandez ML, Potenza M, Gómez KA.
Int J Mol Sci. 2024 Jan 18;25(2):1202. doi: 10.3390/ijms25021202.

Tau reduction with artificial microRNAs modulates neuronal physiology and improves tauopathy phenotypes in mice
Facal CL, Fernández Bessone I, Muñiz JA, Pereyra AE, Pedroncini O, Páez-Paz I, Clerici-Delville R, Arnaiz C, Urrutia L, Falasco G, Argañaraz CV, Saez T, Marin-Burgin A, Soiza-Reilly M, Falzone T, Avale ME.
Mol Ther. 2024 Apr 3;32(4):1080-1095. doi: 10.1016/j.ymthe.2024.01.033. Epub 2024 Feb 3.

Humanized dopamine D(4.7) receptor male mice display risk-taking behavior and deficits of social recognition and working memory in light/dark-dependent manner
Alachkar A, Phan A, Dabbous T, Alhassen S, Alhassen W, Reynolds B, Rubinstein M, Ferré S, Civelli O.
J Neurosci Res. 2024 Feb;102(2):e25299. doi: 10.1002/jnr.25299.

Arabidopsis hypocotyl growth in darkness requires the phosphorylation of a microtubule-associated protein
Arico DS, Burachik NB, Wengier DL, Mazzella MA.
Plant J. 2024 Jun;118(6):1815-1831. doi: 10.1111/tpj.16711. Epub 2024 Mar 17.

Datathons: fostering equitability in data reuse in ecology
Datathon 2022 Consortium:; Jurburg SD, Álvarez Blanco MJ, Chatzinotas A, Kazem A, König-Ries B, Babin D, Smalla K, Cerecetto V, Fernandez-Gnecco G, Covacevich F, Viruel E, Bernaschina Y, Leoni C, Garaycochea S, Terra JA, Fresia P, Figuerola ELM, Wall LG, Covelli JM, Agnello AC, Nieto EE, Festa S, Dominici LE, Allegrini M, Zabaloy MC, Morales ME, Erijman L, Coniglio A, Cassán FD, Nievas S, Roldán DM, Menes R, Jauri PV, Marrero CS, Massa AM, Revetria MAM, Fernández-Scavino A, Pereira-Mora L, Martínez S, Frene JP.
Trends Microbiol. 2024 May;32(5):415-418. doi: 10.1016/j.tim.2024.02.010. Epub 2024 Mar 21.

Tartrate fermentation with H(2) production by a new member of Sporomusaceae enriched from rice paddy soil
Pereira-Mora L, Guerrero LD, Erijman L, Fernández-Scavino A.
Appl Environ Microbiol. 2024 Apr 17;90(4):e0235123. doi: 10.1128/aem.02351-23. Epub 2024 Mar 22.

A maternal dorsoventral prepattern revealed by an asymmetric distribution of ventralizing molecules before fertilization in Xenopus laevis
Castro Colabianchi AM, González Pérez NG, Franchini LF, López SL.
Front Cell Dev Biol. 2024 Mar 20;12:1365705. doi: 10.3389/fcell.2024.1365705. eCollection 2024.

GABAergic synapses between auditory efferent neurons and type II spiral ganglion afferent neurons in the mouse cochlea
Bachman JL, Kitcher SR, Vattino LG, Beaulac HJ, Chaves MG, Rivera IH, Katz E, Wedemeyer C, Weisz CJC.
bioRxiv [Preprint]. 2024 Mar 31:2024.03.28.587185. doi: 10.1101/2024.03.28.587185.

A mammalian tripartite enhancer cluster controls hypothalamic Pomc expression, food intake, and body weight
Rojo D, Hael CE, Soria A, de Souza FSJ, Low MJ, Franchini LF, Rubinstein M.
Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2322692121. doi: 10.1073/pnas.2322692121. Epub 2024 Apr 23.

Production of biologically active human basic fibroblast growth factor (hFGFb) using Nicotiana tabacum transplastomic plants
Müller C, Budnik N, Mirkin FG, Vater CF, Bravo-Almonacid FF, Perez-Castro C, Wirth SA, Segretin ME.
Planta. 2024 Jun 15;260(1):28. doi: 10.1007/s00425-024-04456-5.

Arabidopsis pollen prolyl-hydroxylases P4H4/6 are relevant for correct hydroxylation and secretion of LRX11 in pollen tubes
Sede AR, Wengier DL, Borassi C, Ricardi M, Somoza SC, Aguiló R, Estevez JM, Muschietti JP.
J Exp Bot. 2024 Jul 23;75(14):4415-4427. doi: 10.1093/jxb/erae269.

Accelerated evolution in the human lineage led to gain and loss of transcriptional enhancers in the RBFOX1 locus
Berasain L, Beati P, Trigila AP, Rubinstein M, Franchini LF.
Sci Adv. 2024 Jun 28;10(26):eadl1049. doi: 10.1126/sciadv.adl1049. Epub 2024 Jun 26.

Evaluation and validation of a PrintrLab-based LAMP assay to identify Trypanosoma cruzi in newborns in Bolivia: a proof-of-concept study
Rojas Panozo L, Rivera Nina S, Wehrendt DP, Casellas A, Pinto L, Mendez S, Kuo CW, Lozano DF, Ortiz L, Pinazo MJ, Picado A, Sanz S, Abril M, Gascon J, Wong S, Schijman AG, Torrico F, Alonso-Padilla J.
Lancet Microbe. 2024 Sep;5(9):100887. doi: 10.1016/S2666-5247(24)00110-1. Epub 2024 Jul 3.

Retrospect, advances and challenges in Chagas disease diagnosis: a comprehensive review
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Lancet Reg Health Am. 2024 Jun 20;36:100821. doi: 10.1016/j.lana.2024.100821. eCollection 2024 Aug.

The homeodomain transcription factor Six3 regulates hypothalamic Pomc expression and its absence from POMC neurons induces hyperphagia and mild obesity in male mice
Yu H, Chiang A, Rubinstein M, Low MJ.
Mol Metab. 2024 Sep;87:101993. doi: 10.1016/j.molmet.2024.101993. Epub 2024 Jul 16.

Zoonotic Cycle of American Trypanosomiasis in an Endemic Region of the Argentine Chaco, Factors That Influenced a Paradigm Shift
Gómez-Bravo A, Cirignoli S, Wehrendt D, Schijman A, León CM, Flores-Chaves M, Nieto J, Kieran TJ, Abril M, Guhl F.
Insects. 2024 Jun 25;15(7):471. doi: 10.3390/insects15070471.

Quantitative assessment of the nanoanatomy of the contractile vacuole complex in Trypanosoma cruzi
Augusto I, Girard-Dias W, Schoijet A, Alonso GD, Portugal RV, de Souza W, Jimenez V, Miranda K.
Life Sci Alliance. 2024 Jul 29;7(10):e202402826. doi: 10.26508/lsa.202402826. Print 2024 Oct.

Key role of the TM2-TM3 loop in calcium potentiation of the α9α10 nicotinic acetylcholine receptor
Gallino SL, Agüero L, Boffi JC, Schottlender G, Buonfiglio P, Dalamon V, Marcovich I, Carpaneto A, Craig PO, Plazas PV, Elgoyhen AB.
Cell Mol Life Sci. 2024 Aug 9;81(1):337. doi: 10.1007/s00018-024-05381-2.

Alamandine, a protective component of the renin-angiotensin system, reduces cellular proliferation and interleukin-6 secretion in human macrophages through MasR-MrgDR heteromerization
Rukavina Mikusic NL, Silva MG, Erra Díaz FA, Pineda AM, Ferragut F, Gómez KA, Mazzitelli L, Gonzalez Maglio DH, Nuñez M, Santos RAS, Grecco HE, Gironacci MM.
Biochem Pharmacol. 2024 Nov;229:116480. doi: 10.1016/j.bcp.2024.116480. Epub 2024 Aug 10.

A guide for the generation of repositories of clinical samples for research on Chagas disease
Martínez-Peinado N, Gabaldón-Figueira JC, Rodrigues Ferreira R, Carmen Thomas M, López MC, Cremonini Araújo-Jorge T, Alarcón de Noya B, Berón S, Ramsey J, Losada Galván I, Schijman AG, González Martínez A, Mariano Ruiz A, Rojas G, Magalhães Saraiva R, Noya-González O, Gómez A, Maldonado RA, Pinto J, Torrico F, Scandale I, Agüero F, Pinazo MJ, Gascón J, Hasslocher-Moreno AM, Alonso-Padilla J; NHEPACHA Network (New Tools for the Diagnosis and Evaluation of Chagas Disease).
PLoS Negl Trop Dis. 2024 Aug 15;18(8):e0012166. doi: 10.1371/journal.pntd.0012166. eCollection 2024 Aug.

A standardized clinical database for research in Chagas disease: The NHEPACHA network
González Martínez A, Losada-Galván I, Gabaldón-Figueira JC, Martínez-Peinado N, Saraiva RM, Fernández ML, Ramsey JM, Noya-González O, Alarcón de Noya B, Schijman AG, Berón S, Abril M, Gascón J, Sosa-Estani S, Pinazo MJ, Alonso-Padilla J, Hasslocher-Moreno AM; NHEPACHA network (Nuevas Herramientas para el diagnóstico y la evaluación del paciente con enfermedad de Chagas).
PLoS Negl Trop Dis. 2024 Aug 15;18(8):e0012364. doi: 10.1371/journal.pntd.0012364. eCollection 2024 Aug.

Novel 3D human trophoblast culture to explore T. cruzi infection in the placenta
Apodaca S, Di Salvatore M, Muñoz-Calderón A, Curto MLÁ, Longhi SA, Schijman AG.
Front Cell Infect Microbiol. 2024 Aug 6;14:1433424. doi: 10.3389/fcimb.2024.1433424. eCollection 2024.

Co-release of GABA and ACh from medial olivocochlear neurons fine tunes cochlear efferent inhibition
Castagnola T, Castagna VC, Kitcher SR, Torres Cadenas L, Di Guilmi MN, Gomez Casati ME, Buonfiglio PI, Dalamón V, Katz E, Elgoyhen AB, Weisz CJC, Goutman JD, Wedemeyer C.
bioRxiv [Preprint]. 2024 Aug 16:2024.08.12.607644. doi: 10.1101/2024.08.12.607644.

Plant growth-promoting abilities of Methylobacterium sp. 2A involve auxin-mediated regulation of the root architecture
Grossi CEM, Tani A, Mori IC, Matsuura T, Ulloa RM.
Plant Cell Environ. 2024 Dec;47(12):5343-5357. doi: 10.1111/pce.15116. Epub 2024 Aug 27.

The Human Accelerated Region HAR202 Controls NPAS3 Expression in the Developing Forebrain Displaying Differential Enhancer Activity Between Modern and Archaic Human Sequences
Caporale AL, Cinalli AR, Rubinstein M, Franchini LF.
Mol Biol Evol. 2024 Oct 4;41(10):msae186. doi: 10.1093/molbev/msae186.

Structure-Aided Computational Design of Triazole-Based Targeted Covalent Inhibitors of Cruzipain
Cerutti JP, Diniz LA, Santos VC, Vilchez Larrea SC, Alonso GD, Ferreira RS, Dehaen W, Quevedo MA.
Molecules. 2024 Sep 5;29(17):4224. doi: 10.3390/molecules29174224.

Interlaboratory Harmonization Study and Prospective Evaluation of the PURE-Trypanosoma cruzi-Loop-Mediated Isothermal Amplification Assay for Detecting Parasite DNA in Newborn's Dried Blood Spots
Longhi SA, García-Casares LJ, Muñoz-Calderón A, Irazu L, Rodríguez MA, Landfried G, Alonso-Padilla J, Schijman AG; Chagas-Group.
J Mol Diagn. 2024 Dec;26(12):1055-1064. doi: 10.1016/j.jmoldx.2024.08.007. Epub 2024 Sep 30.

Performance Assessment of ELISA Using the Trypanosoma cruzi-Specific Antigen Tc323 for the Diagnosis of Chronic Chagas Disease
Ossowski MS, Gallardo JP, Chadi R, Hernández Y, Fernández M, Marco JD, Triana-Chavez O, Nolan MS, Pech May A, Ramsey JM, Villar JC, Agüero F, Potenza M, Gómez KA.
ACS Infect Dis. 2024 Dec 13;10(12):4400-4412. doi: 10.1021/acsinfecdis.4c00784. Epub 2024 Nov 16.

Comment on De Rosa et al. Hearing Loss: Genetic Testing, Current Advances and the Situation in Latin America. Genes 2024, 15, 178
Elgoyhen AB, Buonfiglio PI, Dalamón V.
Genes (Basel). 2024 Oct 30;15(11):1401. doi: 10.3390/genes15111401.

Arabidopsis RALF4 Rapidly Halts Pollen Tube Growth by Increasing ROS and Decreasing Calcium Cytoplasmic Tip Levels
Somoza SC, Boccardo NA, Santin F, Sede AR, Wengier DL, Boisson-Dernier A, Muschietti JP.
Biomolecules. 2024 Oct 29;14(11):1375. doi: 10.3390/biom14111375.

Oro-ruminal sampling device and technique for rapid collection of rumen content and improved recovery of solid fractions for microbiome analysis
Miccoli FE, Galarza RI, Juliano N, Ferreyra S, Maresca S, López-Valiente S, Guerrero LD, Palladino RA, Albornoz RI.
JDS Commun. 2024 May 31;5(6):563-567. doi: 10.3168/jdsc.2023-0536. eCollection 2024 Nov.

In silico and in vivo analyses of a novel variant in MYO6 identified in a family with postlingual non-syndromic hearing loss from Argentina
Buonfiglio PI, Bruque CD, Salatino L, Lotersztein V, Pace M, Grinberg S, Elgoyhen AB, Plazas PV, Dalamón V.
NAR Genom Bioinform. 2024 Dec 11;6(4):lqae162. doi: 10.1093/nargab/lqae162. eCollection 2024 Dec.

Discovery of a Potent Triazole-Based Reversible Targeted Covalent Inhibitor of Cruzipain
Cerutti JP, Diniz LA, Corrêa Santos V, Vilchez Larrea SC, Alonso GD, Ferreira RS, Quevedo MA, Dehaen W.
ACS Med Chem Lett. 2024 Dec 23;16(1):72-79. doi: 10.1021/acsmedchemlett.4c00460. eCollection 2025 Jan 9.

A Phase 2, Randomized, Multicenter, Placebo-Controlled, Proof-of-Concept Trial of Oral Fexinidazole in Adults With Chronic Indeterminate Chagas Disease
Torrico F, Gascón J, Ortiz L, Pinto J, Rojas G, Palacios A, Barreira F, Blum B, Schijman AG, Vaillant M, Strub-Wourgaft N, Pinazo MJ, Bilbe G, Ribeiro I.
Clin Infect Dis. 2023 Feb 8;76(3):e1186-e1194. doi: 10.1093/cid/ciac579.

Activation-induced marker assays for identification of Trypanosoma cruzi-specific CD4 or CD8 T cells in chronic Chagas disease patients
Ferragut F, Cruz KM, Gallardo JP, Fernández M, Hernández Vasquez Y, Gómez KA.
Immunology. 2023 Jun;169(2):185-203. doi: 10.1111/imm.13622. Epub 2023 Jan 25.

Expression of Inhibitory Receptors TIGIT, TIM-3, and LAG-3 on CD4+ T Cells from Patients with Different Clinical Forms of Chronic Chagas Disease
Ferragut F, Alcaraz PB, Beati P, Girard MC, Ossowski MS, Chadi R, Fernández M, Hernández-Vásquez Y, Acevedo GR, Gómez KA.
J Immunol. 2023 Mar 1;210(5):568-579. doi: 10.4049/jimmunol.2200436.

The evolutionary tuning of hearing
Lipovsek M, Elgoyhen AB.
Trends Neurosci. 2023 Feb;46(2):110-123. doi: 10.1016/j.tins.2022.12.002. Epub 2023 Jan 6.

The Remarkable Outer Hair Cell: Proceedings of a Symposium in Honour of W. E. Brownell
Ashmore JF, Oghalai JS, Dewey JB, Olson ES, Strimbu CE, Wang Y, Shera CA, Altoè A, Abdala C, Elgoyhen AB, Eatock RA, Raphael RM.
J Assoc Res Otolaryngol. 2023 Apr;24(2):117-127. doi: 10.1007/s10162-022-00852-4. Epub 2023 Jan 17.

Dopaminergic innervation at the central nucleus of the amygdala reveals distinct topographically segregated regions
Casey E, Avale ME, Kravitz A, Rubinstein M.
Brain Struct Funct. 2023 Mar;228(2):663-675. doi: 10.1007/s00429-023-02614-1. Epub 2023 Feb 3.

Structural differences between hypoxanthine phosphoribosyltransferase family members highlight opportunities for antiparasitic drug design in neglected diseases
Santos J, Fernández Villamil SH, Delfino JM, Valsecchi WM.
Arch Biochem Biophys. 2023 Mar 15;737:109550. doi: 10.1016/j.abb.2023.109550. Epub 2023 Feb 14.

Genome-centric metagenomic insights into the role of Chloroflexi in anammox, activated sludge and methanogenic reactors
Bovio-Winkler P, Guerrero LD, Erijman L, Oyarzúa P, Suárez-Ojeda ME, Cabezas A, Etchebehere C.
BMC Microbiol. 2023 Feb 21;23(1):45. doi: 10.1186/s12866-023-02765-5.

Mitochondrial DNA variants in a cohort from Argentina with suspected Leber's hereditary optic neuropathy (LHON)
Buonfiglio PI, Menazzi S, Francipane L, Lotersztein V, Ferreiro V, Elgoyhen AB, Dalamón V.
PLoS One. 2023 Feb 24;18(2):e0275703. doi: 10.1371/journal.pone.0275703. eCollection 2023.

The α9α10 acetylcholine receptor: A non-neuronal nicotinic receptor
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Pharmacol Res. 2023 Apr;190:106735. doi: 10.1016/j.phrs.2023.106735. Epub 2023 Mar 15.

Engineering olivocochlear inhibition to reduce acoustic trauma
Zhang Y, Hiel H, Vincent PFY, Wood MB, Elgoyhen AB, Chien W, Lauer A, Fuchs PA.
Mol Ther Methods Clin Dev. 2023 Feb 26;29:17-31. doi: 10.1016/j.omtm.2023.02.011. eCollection 2023 Jun 8.

Combination of ultra-rapid DNA purification (PURE) and loop-mediated isothermal amplification (LAMP) for rapid detection of Trypanosoma cruzi DNA in dried blood spots
Longhi SA, García Casares LJ, Muñoz-Calderón AA, Alonso-Padilla J, Schijman AG.
PLoS Negl Trop Dis. 2023 Apr 14;17(4):e0011290. doi: 10.1371/journal.pntd.0011290. eCollection 2023 Apr.

Accelerated Evolution Analysis Uncovers PKNOX2 as a Key Transcription Factor in the Mammalian Cochlea
Trigila AP, Castagna VC, Berasain L, Montini D, Rubinstein M, Gomez-Casati ME, Franchini LF.
Mol Biol Evol. 2023 Jul 5;40(7):msad128. doi: 10.1093/molbev/msad128.

[Epidemiological study and serotyping by multiple PCR of Listeria monocytogenes isolated from food matrices in Argentina]
Figueroa Y, Gentiluomo J, Grisaro A, Buffoni M, Zipenco N, Sucari A, Buonfiglio P, Costa M.
Rev Argent Microbiol. 2023 Oct-Dec;55(4):387-394. doi: 10.1016/j.ram.2023.05.004. Epub 2023 Jul 19.

Quantitative PCR-Based Diagnosis and Follow-up of Chagas Disease Primary Infection After Solid Organ Transplant: A Multicentre Study
Barcan LA, Smud A, Besuschio SA, Giorgio PL, Temporiti E, Salgueira C, Pinoni MV, Nagel C, Schijman AG.
J Infect Dis. 2023 Nov 2;228(9):1304-1308. doi: 10.1093/infdis/jiad289.

Molecular Characterization of Trypanosoma cruzi Reactivation and Follow-up in a Case Series of People With HIV
Fernandez ML, Albizu CL, Nicita D, Besuschio S, Giomi C, Biondi ML, Leguizamón MS, Garcia J, Corti M, Schijman A, Burgos JM.
Open Forum Infect Dis. 2023 Jul 10;10(8):ofad357. doi: 10.1093/ofid/ofad357. eCollection 2023 Aug.

Phytosterols reverse antiretroviral-induced hearing loss, with potential implications for cochlear aging
Sodero AO, Castagna VC, Elorza SD, Gonzalez-Rodulfo SM, Paulazo MA, Ballestero JA, Martin MG, Gomez-Casati ME.
PLoS Biol. 2023 Aug 24;21(8):e3002257. doi: 10.1371/journal.pbio.3002257. eCollection 2023 Aug.

Genetic manipulation of protein phosphatase 2A affects multiple agronomic traits and physiological parameters in potato (Solanum tuberosum)
Muñiz García MN, Baroli I, Cortelezzi JI, Zubillaga M, Capiati DA.
Funct Plant Biol. 2023 Dec;50(12):1117-1129. doi: 10.1071/FP23163.

Practical diagnostic algorithms for Chagas disease: a focus on low resource settings
Gabaldón-Figueira JC, Skjefte M, Longhi S, Escabia E, García LJ, Ros-Lucas A, Martínez-Peinado N, Muñoz-Calderón A, Gascón J, Schijman AG, Alonso-Padilla J.
Expert Rev Anti Infect Ther. 2023 Jul-Dec;21(12):1287-1299. doi: 10.1080/14787210.2023.2279110. Epub 2023 Nov 24.

Improving genome-wide mapping of nucleosomes in Trypanosome cruzi
Beati P, Massimino Stepñicka M, Vilchez Larrea SC, Smircich P, Alonso GD, Ocampo J.
PLoS One. 2023 Nov 21;18(11):e0293809. doi: 10.1371/journal.pone.0293809. eCollection 2023.

Novel Pathogenic Variants in the Gene Encoding Stereocilin (STRC) Causing Non-Syndromic Moderate Hearing Loss in Spanish and Argentinean Subjects
Domínguez-Ruiz M, Ruiz-Palmero L, Buonfiglio PI, García-Vaquero I, Gómez-Rosas E, Goñi M, Villamar M, Morín M, Moreno-Pelayo MA, Elgoyhen AB, Del Castillo FJ, Dalamón V, Del Castillo I.
Biomedicines. 2023 Oct 31;11(11):2943. doi: 10.3390/biomedicines11112943.

Unveiling challenges in real-time PCR strategies for detecting treatment failure: observations from clinical trials on chronic Chagas disease
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Front Parasitol. 2023 Sep 26;2:1260224. doi: 10.3389/fpara.2023.1260224. eCollection 2023.

Calcium-dependent protein kinase 2 plays a positive role in the salt stress response in potato
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Plant Cell Rep. 2022 Mar;41(3):535-548. doi: 10.1007/s00299-021-02676-7. Epub 2021 Mar 2.

Extracellular hydrolytic potential drives microbiome shifts during anaerobic co-digestion of sewage sludge and food waste
Orellana E, Guerrero LD, Davies-Sala C, Altina M, Pontiggia RM, Erijman L.
Bioresour Technol. 2022 Jan;343:126102. doi: 10.1016/j.biortech.2021.126102. Epub 2021 Oct 8.

Homology Modeling and Molecular Dynamics Simulations of Trypanosoma cruzi Phosphodiesterase b1
Llanos MA, Alberca LN, Larrea SCV, Schoijet AC, Alonso GD, Bellera CL, Gavenet L, Talevi A.
Chem Biodivers. 2022 Jan;19(1):e202100712. doi: 10.1002/cbdv.202100712. Epub 2021 Dec 16.

Genetic polymorphism of Trypanosoma cruzi bloodstream populations in adult chronic indeterminate Chagas disease patients from the E1224 clinical trial
Ramírez JC, Acevedo GR, Torres C, Parrado R, De La Barra A, Villarroel S, García L, Gascon J, Ortiz L, Torrico F, Ribeiro I, Schijman AG.
J Antimicrob Chemother. 2022 Feb 23;77(3):578-584. doi: 10.1093/jac/dkab446.

Predicting pathogenicity for novel hearing loss mutations based on genetic and protein structure approaches
Buonfiglio PI, Bruque CD, Lotersztein V, Luce L, Giliberto F, Menazzi S, Francipane L, Paoli B, Goldschmidt E, Elgoyhen AB, Dalamón V.
Sci Rep. 2022 Jan 7;12(1):301. doi: 10.1038/s41598-021-04081-2.

Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes
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Elife. 2022 Jan 19;11:e72883. doi: 10.7554/eLife.72883.

Galectins in Chagas Disease: A Missing Link Between Trypanosoma cruzi Infection, Inflammation, and Tissue Damage
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Front Microbiol. 2022 Jan 3;12:794765. doi: 10.3389/fmicb.2021.794765. eCollection 2021.

Behavioral and Neuroanatomical Consequences of Cell-Type Specific Loss of Dopamine D2 Receptors in the Mouse Cerebral Cortex
Lee GS, Graham DL, Noble BL, Trammell TS, McCarthy DM, Anderson LR, Rubinstein M, Bhide PG, Stanwood GD.
Front Behav Neurosci. 2022 Jan 13;15:815713. doi: 10.3389/fnbeh.2021.815713. eCollection 2021.

Partial Ablation of Postsynaptic Dopamine D2 Receptors in the Central Nucleus of the Amygdala Increases Risk Avoidance in Exploratory Tasks
Casey E, Avale ME, Kravitz A, Rubinstein M.
eNeuro. 2022 Mar 15;9(2):ENEURO.0528-21.2022. doi: 10.1523/ENEURO.0528-21.2022. Print 2022 Mar-Apr.

The α9α10 nicotinic acetylcholine receptor: a compelling drug target for hearing loss?
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Expert Opin Ther Targets. 2022 Mar;26(3):291-302. doi: 10.1080/14728222.2022.2047931. Epub 2022 Mar 7.

Microbiomes and glyphosate biodegradation in edaphic and aquatic environments: recent issues and trends
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World J Microbiol Biotechnol. 2022 Apr 28;38(6):98. doi: 10.1007/s11274-022-03281-w.

Parasitological, serological and molecular diagnosis of acute and chronic Chagas disease: from field to laboratory
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Mem Inst Oswaldo Cruz. 2022 May 23;117:e200444. doi: 10.1590/0074-02760200444. eCollection 2022.

Loop-Mediated Isothermal Amplification of Trypanosoma cruzi DNA for Point-of-Care Follow-Up of Anti-Parasitic Treatment of Chagas Disease
Muñoz-Calderón AA, Besuschio SA, Wong S, Fernández M, García Cáceres LJ, Giorgio P, Barcan LA, Markham C, Liu YE, de Noya BA, Longhi SA, Schijman AG.
Microorganisms. 2022 Apr 26;10(5):909. doi: 10.3390/microorganisms10050909.

Cerebellar dopamine D2 receptors regulate social behaviors
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Nat Neurosci. 2022 Jul;25(7):900-911. doi: 10.1038/s41593-022-01092-8. Epub 2022 Jun 16.

The Kinetoplastid-Specific Protein TcCAL1 Plays Different Roles During In Vitro Differentiation and Host-Cell Invasion in Trypanosoma cruzi
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Dopamine D2Rs coordinate cue-evoked changes in striatal acetylcholine levels
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Editorial: Signaling in stress sensing and resistance in parasitic protozoa
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Architecture, Chromatin and Gene Organization of Toxoplasma gondii Subtelomeres
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Keeping up with the RALFs: how these small peptides control pollen-pistil interactions in Arabidopsis
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Unraveling the Molecular Players at the Cholinergic Efferent Synapse of the Zebrafish Lateral Line
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J Neurosci. 2021 Jan 27;41(4):594-612. doi: 10.1523/JNEUROSCI.2178-20.2020. Epub 2020 Dec 10.

Development and Evaluation of a Three-Dimensional Printer-Based DNA Extraction Method Coupled to Loop Mediated Isothermal Amplification for Point-of-Care Diagnosis of Congenital Chagas Disease in Endemic Regions
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The cytosolic tryparedoxin peroxidase from Trypanosoma cruzi induces a pro-inflammatory Th1 immune response in a peroxidatic cysteine-dependent manner
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Immunology. 2021 May;163(1):46-59. doi: 10.1111/imm.13302. Epub 2021 Jan 25.

Recombinant antibody against Trypanosoma cruzi from patients with chronic Chagas heart disease recognizes mammalian nervous system
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Epigenetics Chromatin. 2021 Jan 11;14(1):5. doi: 10.1186/s13072-020-00381-5.

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Biol Open. 2021 Feb 25;10(2):bio051797. doi: 10.1242/bio.051797.

Impacts of switching tillage to no-tillage and vice versa on soil structure, enzyme activities and prokaryotic community profiles in Argentinean semi-arid soils
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Loss of Choline Agonism in the Inner Ear Hair Cell Nicotinic Acetylcholine Receptor Linked to the α10 Subunit
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Towards a unification of treatments and interventions for tinnitus patients: The EU research and innovation action UNITI
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Tinnitus and tinnitus disorder: Theoretical and operational definitions (an international multidisciplinary proposal)
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Genetic Mechanisms Underlying Cortical Evolution in Mammals
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Front Cell Dev Biol. 2021 Feb 15;9:591017. doi: 10.3389/fcell.2021.591017. eCollection 2021.

Interaction Between the Angiotensin-(1-7) Mas Receptor and the Dopamine D2 Receptor: Implications in Inflammation
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Hypertension. 2021 May 5;77(5):1659-1669. doi: 10.1161/HYPERTENSIONAHA.120.16614. Epub 2021 Mar 8.

Zoledronate repositioning as a potential trypanocidal drug. Trypanosoma cruzi HPRT an alternative target to be considered
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Biochem Pharmacol. 2021 Jun;188:114524. doi: 10.1016/j.bcp.2021.114524. Epub 2021 Mar 17.

Ex vivo characterization of Breg cells in patients with chronic Chagas disease
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Sci Rep. 2021 Mar 9;11(1):5511. doi: 10.1038/s41598-021-84765-x.

Characterization of two group III potato CDPKs, StCDPK22 and StCDPK24, that contain three EF-Hand motifs in their CLDs
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Plant Physiol Biochem. 2021 May;162:716-729. doi: 10.1016/j.plaphy.2021.03.008. Epub 2021 Mar 9.

Glyphosate Biodegradation Potential in Soil Based on Glycine Oxidase Gene (thiO) from Bradyrhizobium
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Curr Microbiol. 2021 May;78(5):1991-2000. doi: 10.1007/s00284-021-02467-z. Epub 2021 Apr 2.

Characterization of Developmental Changes in Spontaneous Electrical Activity of Medial Superior Olivary Neurons Before Hearing Onset With a Combination of Injectable and Volatile Anesthesia
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Front Neurosci. 2021 Apr 15;15:654479. doi: 10.3389/fnins.2021.654479. eCollection 2021.

Characterization and Follow-Up of Trypanosoma cruzi Natural Populations Refractory to Etiological Chemotherapy in Oral Chagas Disease Patients
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Front Cell Infect Microbiol. 2021 Apr 28;11:665063. doi: 10.3389/fcimb.2021.665063. eCollection 2021.

An AMP-activated protein kinase complex with two distinctive alpha subunits is involved in nutritional stress responses in Trypanosoma cruzi
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Editorial: Meta-omic Approaches to the Complex Anaerobic Communities in Wastewater Treatment Plants and Digesters
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Front Microbiol. 2021 May 7;12:664716. doi: 10.3389/fmicb.2021.664716. eCollection 2021.

Tau mis-splicing correlates with motor impairments and striatal dysfunction in a model of tauopathy
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Brain. 2021 Sep 4;144(8):2302-2309. doi: 10.1093/brain/awab130.

Serological reactivity against T. cruzi-derived antigens: Evaluation of their suitability for the assessment of response to treatment in chronic Chagas disease
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Acta Trop. 2021 Sep;221:105990. doi: 10.1016/j.actatropica.2021.105990. Epub 2021 Jun 6.

Fyn knockdown prevents levodopa-induced dyskinesia in a mouse model of Parkinson's disease
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eNeuro. 2021 Jun 7;8(4):ENEURO.0559-20.2021. doi: 10.1523/ENEURO.0559-20.2021. Online ahead of print.

First body of evidence suggesting a role of a tankyrase-binding motif (TBM) of vinculin (VCL) in epithelial cells
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PeerJ. 2021 May 27;9:e11442. doi: 10.7717/peerj.11442. eCollection 2021.

Theragnosis for Duchenne Muscular Dystrophy
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Front Pharmacol. 2021 Jun 3;12:648390. doi: 10.3389/fphar.2021.648390. eCollection 2021.

Prospective multicenter evaluation of real time PCR Kit prototype for early diagnosis of congenital Chagas disease
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EBioMedicine. 2021 Jul;69:103450. doi: 10.1016/j.ebiom.2021.103450. Epub 2021 Jun 26.

Chloroplasts alter their morphology and accumulate at the pathogen interface during infection by Phytophthora infestans
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Plant J. 2021 Sep;107(6):1771-1787. doi: 10.1111/tpj.15416. Epub 2021 Aug 12.

Synaptic Contributions to Cochlear Outer Hair Cell Ca(2+) Dynamics
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J Neurosci. 2021 Aug 11;41(32):6812-6821. doi: 10.1523/JNEUROSCI.3008-20.2021. Epub 2021 Jul 12.

T Cell Specificity: A Great Challenge in Chagas Disease
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Front Immunol. 2021 Jun 29;12:674078. doi: 10.3389/fimmu.2021.674078. eCollection 2021.

Author Correction: Expression of pathogenesis-related proteins in transplastomic tobacco plants confers resistance to filamentous pathogens under field trials
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Sci Rep. 2021 Aug 5;11(1):16294. doi: 10.1038/s41598-021-95177-2.

IgE antibodies against Trypanosoma cruzi arginine kinase in patients with chronic Chagas disease
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Mol Immunol. 2021 Oct;138:68-75. doi: 10.1016/j.molimm.2021.06.024. Epub 2021 Aug 4.

Proline-rich extensin-like receptor kinases PERK5 and PERK12 are involved in pollen tube growth
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FEBS Lett. 2021 Oct;595(20):2593-2607. doi: 10.1002/1873-3468.14185. Epub 2021 Sep 5.

A rapid and simple protocol for concentration of SARS-CoV-2 from sewage
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J Virol Methods. 2021 Nov;297:114272. doi: 10.1016/j.jviromet.2021.114272. Epub 2021 Aug 26.

Trypanosoma cruzi Induces Regulatory B Cell Alterations in Patients With Chronic Chagas Disease
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Front Cell Infect Microbiol. 2021 Aug 12;11:723549. doi: 10.3389/fcimb.2021.723549. eCollection 2021.

In vitro differentiation of Trypanosoma cruzi epimastigotes into metacyclic trypomastigotes using a biphasic medium
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STAR Protoc. 2021 Sep 1;2(3):100703. doi: 10.1016/j.xpro.2021.100703. eCollection 2021 Sep 17.

Noise Exposure Potentiates Exocytosis From Cochlear Inner Hair Cells
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Front Synaptic Neurosci. 2021 Sep 29;13:740368. doi: 10.3389/fnsyn.2021.740368. eCollection 2021.

A Single Dose of a Hybrid hAdV5-Based Anti-COVID-19 Vaccine Induces a Long-Lasting Immune Response and Broad Coverage against VOC
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The Cholinergic Lateral Line Efferent Synapse: Structural, Functional and Molecular Similarities With Those of the Cochlea
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Front Cell Neurosci. 2021 Oct 12;15:765083. doi: 10.3389/fncel.2021.765083. eCollection 2021.

Hearing loss genes reveal patterns of adaptive evolution at the coding and non-coding levels in mammals
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BMC Biol. 2021 Nov 16;19(1):244. doi: 10.1186/s12915-021-01170-6.

Homecoming: rewinding the reductive evolution of the chloroplast genome for increasing crop yields
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Nat Commun. 2021 Nov 18;12(1):6734. doi: 10.1038/s41467-021-26975-5.

The Hair Cell α9α10 Nicotinic Acetylcholine Receptor: Odd Cousin in an Old Family
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Front Cell Neurosci. 2021 Nov 15;15:785265. doi: 10.3389/fncel.2021.785265. eCollection 2021.

A novel strategy to uncover specific GO terms/phosphorylation pathways in phosphoproteomic data in Arabidopsis thaliana
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BMC Plant Biol. 2021 Dec 14;21(1):592. doi: 10.1186/s12870-021-03377-9.

New chemotherapy regimens and biomarkers for Chagas disease: the rationale and design of the TESEO study, an open-label, randomised, prospective, phase-2 clinical trial in the Plurinational State of Bolivia
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Tankyrase inhibitors hinder Trypanosoma cruzi infection by altering host-cell signalling pathways
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Parasitology. 2021 Nov;148(13):1680-1690. doi: 10.1017/S0031182021001402. Epub 2021 Aug 12.

Differential tissue distribution of discrete typing units after drug combination therapy in experimental Trypanosoma cruzi mixed infection
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Poly(ADP-ribose) metabolism in human parasitic protozoa
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New Scheme of Intermittent Benznidazole Administration in Patients Chronically Infected with Trypanosoma cruzi: Clinical, Parasitological, and Serological Assessment after Three Years of Follow-Up
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Antimicrob Agents Chemother. 2020 Aug 20;64(9):e00439-20. doi: 10.1128/AAC.00439-20. Print 2020 Aug 20.

Interplay among ATP-Dependent Chromatin Remodelers Determines Chromatin Organisation in Yeast
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Biology (Basel). 2020 Jul 25;9(8):190. doi: 10.3390/biology9080190.

Trypanosoma cruzi loop-mediated isothermal amplification (Trypanosoma cruzi Loopamp) kit for detection of congenital, acute and Chagas disease reactivation
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PLoS Negl Trop Dis. 2020 Aug 14;14(8):e0008402. doi: 10.1371/journal.pntd.0008402. eCollection 2020 Aug.

Short-course Benznidazole treatment to reduce Trypanosoma cruzi parasitic load in women of reproductive age (BETTY): a non-inferiority randomized controlled trial study protocol
Cafferata ML, Toscani MA, Althabe F, Belizán JM, Bergel E, Berrueta M, Capparelli EV, Ciganda Á, Danesi E, Dumonteil E, Gibbons L, Gulayin PE, Herrera C, Momper JD, Rossi S, Shaffer JG, Schijman AG, Sosa-Estani S, Stella CB, Klein K, Buekens P.
Reprod Health. 2020 Aug 24;17(1):128. doi: 10.1186/s12978-020-00972-1.

Mouse models for V103I and I251L gain of function variants of the human MC4R display decreased adiposity but are not protected against a hypercaloric diet
Rojo D, McCarthy C, Raingo J, Rubinstein M.
Mol Metab. 2020 Dec;42:101077. doi: 10.1016/j.molmet.2020.101077. Epub 2020 Sep 9.

Functional redundancy and compensation: Deletion of multiple murine Crisp genes reveals their essential role for male fertility
Curci L, Brukman NG, Weigel Muñoz M, Rojo D, Carvajal G, Sulzyk V, Gonzalez SN, Rubinstein M, Da Ros VG, Cuasnicú PS.
FASEB J. 2020 Dec;34(12):15718-15733. doi: 10.1096/fj.202001406R. Epub 2020 Oct 10.

GJB2 and GJB6 Genetic Variant Curation in an Argentinean Non-Syndromic Hearing-Impaired Cohort
Buonfiglio P, Bruque CD, Luce L, Giliberto F, Lotersztein V, Menazzi S, Paoli B, Elgoyhen AB, Dalamón V.
Genes (Basel). 2020 Oct 21;11(10):1233. doi: 10.3390/genes11101233.

PARP Inhibitor Olaparib Causes No Potentiation of the Bleomycin Effect in VERO Cells, Even in the Presence of Pooled ATM, DNA-PK, and LigIV Inhibitors
Perini V, Schacke M, Liddle P, Vilchez-Larrea S, Keszenman DJ, Lafon-Hughes L.
Int J Mol Sci. 2020 Nov 5;21(21):8288. doi: 10.3390/ijms21218288.